Bioinformatics Programmer II

Position: Bioinformatics Programmer II

Job ID: 403467

Location: US-TX-Houston

Department: Lab - Administration

Talent Area: Information Services

Full/Part Time: Full time

Regular/Temporary: Regular

Shift: 8a - 5p

About Texas Children's Hospital

Since 1954, Texas Children’s has been leading the charge in patient care, education and research to accelerate health care for children and women around the world. When you love what you do, it truly shows in the smiles of our patient families, employees and our numerous accolades such as being consistently ranked as the best children’s hospital in Texas, and among the top in the nation by U.S.News & World Report as well as recognition from Houston Business Journal as one of this city’s Best Places to Work for ten consecutive years.

Texas Children’s comprehensive health care network includes our primary hospital in the Texas Medical Center with expertise in over 40 pediatric subspecialties; the Jan and Dan Duncan Neurological Research Institute (NRI); the Feigin Center for pediatric research; Texas Children’s Pavilion for Women, a comprehensive obstetrics/gynecology facility focusing on high-risk births; Texas Children’s Hospital West Campus, a community hospital in suburban West Houston; and Texas Children’s Hospital The Woodlands, a second community hospital opening in 2017. We have also created the nation’s first HMO for children, established the largest pediatric primary care network in the country and a global health program that is channeling care to children and women all over the world. Texas Children’s Hospital is also academically affiliated with Baylor College of Medicine, one of the largest, most diverse and successful pediatric programs in the nation.

To join our community of 13,000 dedicated team members, visit for career opportunities. You can also learn more about our amazing culture at


The Bioinformatics Programmer II works with limited supervision to formulate and define project scope and objectives through investigation and fact finding to develop or modify complex information systems handling biological data. He/she uses knowledge of molecular biology and computer science to manipulate and process complex data sets. Data management involves capturing information pertaining to biological and cellular activities captured using molecular biology methods, which may include microarray and next-generation sequencing.

- Provides analysis for the design and modification of bioinformatics solutions.
- Provides technical expertise in the implementation and modification of bioinformatics solutions.
- Implements and controls the configuration, development, and maintenance of bioinformatics solutions.
- Administers program and system tests.
- Develops system documentation.
- Remains aware of any upcoming system enhancements.
- Prepares reports.
- Troubleshoots and documents disruptions, providing a focal point for coordinating user and vendor support.

Knowledge and Skills
• Experience with Python, databases and SQL
• Familiarity with the development cycle: build, debug, test, deploy, validate, document, maintain production-level software
• Familiarity with version control systems, continuous integration processes, reproducibility, data analysis and manipulation of data sets
• Working knowledge of object-oriented Python and familiarity with packages like biopython, pandas, numpy, scikit-learn and django
• Familiarity with web interfaces, bioinformatics databases, Illumina based NGS methods and tools
• Familiarity with variant detection in oncology
• Familiarity with other languages, e.g. R, C++, VBA
• Knowledge of current laboratory practices and computing systems, interfaces, and current standard software.
• Project management and planning, leadership skills, excellent written and verbal communication, analytical, and organizational skills, ability to analyze the functionality of systems and their fit with specifications, and the ability to work independently with minimum supervision.
• Key skills are observation, results oriented, and communication.


Being fully vaccinated against COVID-19, including any booster dose(s) of the COVID-19 vaccine recommended by the Centers for Disease Control when eligible, is required for all employees at Texas Children’s, unless approved for a medical or religious exemption.

- Bachelor's Degree Biological science, Computer science, Computational/programming, or related technical area required
- Master's Degree Biological Science, Computational/Programming, Computer science, or related field preferred

- 2 years Relevant bioinformatics experience in a clinical setting


Apply Now
Current Texas Children’s employees – Please click here to login.
Create Profile or Log In Search Careers